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3 . 2015

Experimental investigation of the strength of the mitral valve in degenerative diseases

Abstract

Renaissance of the reconstructive surgery of atrioventricular valves which has brought up lots of open questions makes this survey especially relevant. Due to the experimental tests our survey studies normal strength properties of mitral valve structures, various forms of mitral degenerative diseases and properties of repaired mitral valve structures.

We found that strength of the normal mitral valve leaflets is equal in all segments, whereas degenerative diseases are marked by local strength decrease of some segments.

During the experiment we showed criticality of decrease chordae strength properties, when under conditions of physiological stress chordae was fractured. We found that normal chordae have fourfold strength reserve, 74.2% fall of strength reserve causes chordae's fracture.

In groups of intact chordae in Barlow disease and fibroelastic deficiency dangerous decrease of strength was not found. In cases of Barlow disease maximum tension in intact chordae is 13.2% less then in normal chordae. In cases of fibroelastic deficiency maximum tension is 30.5% less then in normal chordae. Foregoing premises allow us to consider that decrease of intact chordae strength in cases of connective tissue diseases is not critical and therefore chordae could function in vivo after mitral valve repair.

Keywords:mitral valve, strength properties, degenerative pathologies

Clin. Experiment. Surg. Petrovsky J. 2015. № 3. Р. 18–24.

References

1. Bokeria L.A. Cardiovascular surgery // A.N. Bakulev SCCVS. Moscow, 2006. (in Russian)

2. Bokeria L.A. Cardiovascular surgery // A.N. Bakulev SCCVS. Moscow, 2007. (in Russian)

3. Bokeria L.A. Cardiovascular surgery // A.N. Bakulev SCCVS. Moscow, 2010. (in Russian)

4. Bokeria L.A. Cardiovascular surgery // A.N. Bakulev SCCVS. Moscow, 2013. (in Russian)

5. Dzemeshkevich S., Stevenson L.U. Mitral valve deseases. Function, diagnostics, treatment. 2st ed. Moscow: GEOTAR-Media, 2015: 287. (in Russian)

6. Ivanov V.A., Aydamirov Ya.A., Evseev E.P., Podchasov D.A. The immediate results of mitral valve replacement in patients elderly. Kardiologiya i serdechno-sosudistaya khirurgiya [Cardiology and Car- diovascular Surgery]. 2014; Vol. 3: 49–52. (in Russian)

7. Ivanov V.A., Popov S.O. Remodeling of the left ventricle at mi- tral valve replacement. Meditsinskiy vestnik Bashkortostana [Medical bulletin of Bashkortostan]. 2013; Vol. 8, N 6: 56–60. (in Russian)

8. Marchenko S.P. Reconstructive surgery of atrioventricular valves of the heart. Autoabstract of Diss. Saint Petersburg, 2009. (in Russian)

9. Mitrofanova L.B. Clinical and morphological features of the heart with valvular various etiologies. Autoabstract of Diss. Saint Pe- tersburg, 2005. 37 р. (in Russian)

10. Skopin I.I., Mironenko V.A., Aliev Sh.M. Repeated interven- tions after reconstructive surgery on the mitral valve. Byulleten’ nauch- nogo tsentra serdechno-sosudistoy khirurgii [Bulletin of Scientific Cen- ter for Cardiovascular Surgery]. 2005. Vol. 6, N 6: 47–52. (in Russian)

11. Skopin I.I., Mironenko V.A., Makushkin A.A., et al. Recon- struction of subvalvular structures yarn of polytetrafluoroethylene (ePTFE) during mitral valve replacement. Grudnaya i serdechno- sosudistaya khirurgiya [Thoracic and Cardiovascular Surgery] 2003; Vol. 1: 23–9. (in Russian)

12. Hubulava, G.G. Modern reconstructive valve technology / G.G. Hubulava, N.N. Shikhverdiev, S.P. Marchenko i dr. Saint Peters- burg, 2006. 90 р.

13. Shikhverdiev, N.N. Fundamentals of reconstructive surgery of heart valves / N.N. Shikhverdiev, S.P. Marchenko. – SPb.: Diton, 2007. – 270 p.

14. Saint Petersburg, Diton, 2007. 270 р. (in Russian)

15. Shikhverdiev N.N., Hubulava G.G., Marchenko S.P. Of valve surgery in mitral surgery infectious etiology: indications and options for correction / Kardiostim 2004. Vestnik aritmologii [Bulletin of ar- rhythmology]2004; Vol. 35, suppl. А: 166. (in Russian)

16. Shumakov V.I. Surgical correction of mitral valve insuffi- ciency: experimental- anatomical study: Autoabstract of Diss. Mos- cow, 1959. 18 р. (in Russian)

17. ACC/AHA 2006 practice guidelines for the management of patients with valvular heart disease. J Am Coll Cardiol. 2006; Vol. 48, N 4: 598–675.

18. Barlow C., Ali Z.A., Lim E., et al. Modified technique for mitral repair without ring annuloplasty. Ann Thorac Surg. 2003; Vol. 75, N 1: 298–300.

19. Carpentier A. Carpentier’s Reconstructive Valve Sur- gery: from Valve Analysis to Valve Reconstruction. W.B. Saunders,

2010.

20. Nielsen S., Timek T., Green R. Influence of anterior mitral

leaflet second-chordae tendineae on left ventricular systolic func- tion. Circulation. 2003; Vol. 108, N 2: 486–91.

21. Rechid Z. Reoperation for failure of mitral valve repair in degenerative disease: a single-center experience. Ann Thorac Surg. 2008; Vol. 86: 1480–4.

22. Lim S.D., Reynolds M.R. et al. Improved functional status and quality of life in prohibitive surgical risk patients with degenera- tive mitral regurgitation after transcatheter mitral valve repair. J Am Coll Cardiol. 2014; Vol. 64, N 2.

23. SuriR.M.,etal.Survivaladvantageandimproveddurability of mitral repair for leaflet prolapse subsets in the current era. Ann Thorac Surg. 2006; Vol. 82, N 3: 819–26.

24. Tsuyoshi K., Cohn L.H. Mitral valve repair – evolution and revolution 1923–2013. Circ J. 2014; Vol. 78: 560–6.

25. Tesler U.F., Lanzillo G., Cerin G. Feasibility of mitral valve repair for degenerative insufficiency involving both leaflets. Interac Card Vasc Thorac Surg. 2006; Vol. 5, suppl. 2: 220.

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CHIEF EDITOR
CHIEF EDITOR
Sergey L. Dzemeshkevich
MD, Professor (Moscow, Russia)

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