Angelina Jolie's casus and ethical problems of modern oncology
Abstract This article discusses some of moral problems of modern oncology, related to development the targeted approach, the desire to personalize predictive (diagnostic) methods and preventive health interventions. It notes the role of the commercialization in the formation of new models of the relationship between doctors and patients. As a representative illustrative example is considered a case of the American movie star A. Jolie. The influence of her publications on the decision to have a preventive mastectomy in woman is presented.
Keywords:moral problems
of oncology, effective targeted approach, Angelina Jolie, BRCA1, testing, screening, breast cancer, prophylactic mastectomy
Clin. Experiment. Surg. Petrovsky J. 2015. № 4. Р. 5–11.
1. Gerasimenko V.N., Tkhostov A., Cosciug N.G. Social attitudes to cancer patients. Voprosy onkologii [Questions of Oncology]. 1986; Vol. XXXII (11): 50–4. (in Russian)
2. Bovina I.B., Bovin B.G. Stigma: social psychological aspects (part 2) [Electronic resource]. Psikhologiya i pravo [Psychology and Law]. 2013; N 4. URL: http://psyjournals.ru/psyandlaw/2013/ n4/66185.shtml (reference date: 29.10.2015) (in Russian)
3. Demin V.E. Society and cancer. The search for understanding. Voprosy onkologii [Questions of Oncology]. 2009; Vol. 45 (6): 701–5. (in Russian)
4. The final document and recommendations UNESCO Conference "Social Justice in Healthcare: Bioethics and Human Rights", Moscow, 7–8 December 2005. Znanie. Ponimanie. Umenie [Knowledge. Understanding. Skill]. 2006; N 2: 128–35. (in Russian)
5. Chulkov V.A., Pesterev E.V. Sociopsychological aspects of cancer in modern society. Sotsial'naya psikhologiya i obshchestvo [Social Psychology and Society]. 2015; Vol. 6 (1): 117–25. (in Russian)
6. Gevandova M.G., Amlaev K.R., Sidorov D.V. Ethical characteristics of the communication of the diagnosis to the patient Oncology practice. Bioetika [Bioethics]. 2015; Vol. 2 (16): 55–9. (in Russian)
7. Potter V.R. Bioethics: Bridge to the Future. Prentice- Hall, 1971.
8. Holland J., Lederberg M., O’hare D. Bioethics in oncology: An international perspective October 15–16, 1992 European School of Oncology. Psychooncology. 1993; Vol. 2, Issue 1: 63–6.
9.Biomedical Humanities URL: http://www.ieo.it/en /RESEARCH/Medical-Humanities/Biomedical-Humanities/ (reference date: 24.10.2015).
10. Davydov M.I., Axel E.M. Statistics of malignant neoplasms in Russia and CIS in 2012. Moscow, 2014: 14. (in Russian)
11. A statement of the case Angelina Jolie is given in two articles published in and "Experts Back Angelina Jolie Pitt in Choices for Cancer Prevention" NYT, March 24, 2015. URL: http://nyti.ms/1HBTrv1 (reference date: 14.09.2015).
12. The New York Times. "My Medical Choice". NYT, May 14, 2013. URL: http://nyti.ms/19l8bbY (reference date: 14.09.2015).
13. Jolie Pitt A. Angelina Jolie Pitt: Diary of a Surgery. NYT, March 24, 2015.
14. Armstrong D., Lilford R., Ogden J. Health-related Quality of Life and the Transformation of Symptoms. Sociology of Health & Illness. 2007; Vol. 29: 570–83.
15. Surgery to Reduce the Risk of Breast Cancer. URL: http://www.cancer.gov/types/breast/risk-reducing-surgery-fact-sheet (reference date: 24.10.2015).
16. Lostumbo L., Carbine N.E., Wallace J. Prophylactic mastectomy for the prevention of breast cancer. Cochrane Database Syst. Rev. 2010 Nov 10. Issue 11.
17. List M. The "Jolie Effect": Managing Awareness, Risk, and Personal Choices. URL: http://msubioethics.com/2013/06/11/the-jolie-effect-managing-awareness-risk-and-personal-choices-2/ (reference date: 26.10.2015).
18. Lebo P.B., Quehenberger F., Kamolz L.-P., Lumenta D.B. The Angelina effect revisited: Exploring a media-related impact on public awareness. Cancer. 2015. doi: 10.1002/cncr.29461.
19. Sell D. Angelina Jolie, breast cancer testing, Myriad Ge- netics and the Supreme Court. URL: http://www.philly.com/philly/blogs/phillypharma/Angelina-Jolie-breast-cancer-testing-Myriad- Genetics-and-the-Supreme-Court.html#dsAFtf1f2LFIvrD6.99
20. Benn P.A., Chapman A.R. Ethical challenges in providing noninvasive prenatal diagnostics. Curr Opin Obstet Gynecol. 2010; Vol. 22: 128–34.
21. Izhevskaya V., Bochkov N.P. Ethical issues of medical genetics. In the book "Hereditary diseases: national guidelines". Ed. by Acad. RAMS N.P. Bochkova, Acad. Of RAMS E.K. Ginter, Acad. of RAMS V.P. Puzyreva. Moscow: GEOTAR-Media, 2012: 888–27. (in Russian)
22. van El C.G., Cornel M.C., Borry P.et al. Whole genome sequencing in health care recommendations of the ESHG. Eur J Hum Genet. 2013; Vol. 21: 580–4; doi:10.1038/ejhg.2013.46.
23. Imyanitov E.N. The General idea of targeted therapy. Prakticheskaya onkologiya [Practical Oncology]. 2010; Vol. 11. N 3: 123–30. (in Russian)
24. The list of medical technologies permitted for use in medi- cal practice on December 30, 2011. http://www.roszdravnadzor.ru/i/upload/images/2015/8/17/1439815946.74935-1-607.xlsx. (in Russian)
25. Porter R. Hospitals and surgery. The Cambridge Illustrated History of Medicine. Cambridge University Press, 1996: 233–4.
26. Ball C.G., Kirkpatrick A.W., Williams D.R. Prophylactic surgery prior to extended-duration space flight: is the benefit worth the risk? Can J Surg. 2012; Vol. 55, N 2: 125–31.
27. Video of some performances are available on the website RUSSCO UTL: http://www.rosoncoweb.ru/events/2014/01/22/archive.
28. Sarah T. Hawley, Reshma Jagsi, Monica Morrow, Nancy K. Janz, et al. Social and Clinical determinants of contralateral prophylactic mastectomy. JAMA Surg. 2014; Vol. 149, N 6: 582–9.
29. Brown R., Butow P., Wilson-Genderson M., Bernhard J., et al. Meeting the decision-making preferences of patients with breast cancer in oncology consultations: impact on decision-related outcomes. J Clin Oncol. 2012; Vol. 30 (8): 857–62.