Sepsis – definitions and diagnostics criteria: evolution of views on the issue
Abstract This review is an analysis of the evolution of the concept of sepsis for the last 25 years with regard to the relationships between pathogenesis, clinical and laboratory data. We considered definitions and diagnostic criteria for sepsis, which have been changed due to deeper understanding of the pathogenetic process, and which have been modified for the sake of possible rapid diagnostics and immediate treatment. In current work we pay special attention to multidisciplinary diagnostic criteria and monitoring of septic process. We concluded the importance of treating any patient as a unique case and patient-tailored treatment based on the assessment of clinical status and integrated approach based in its turn on scientific knowledge and accepted protocols.
Keywords:sepsis, SIRS, multiple organ failure, biomarkers, lactate, pCO2v-a, deformity of the left ventricle
Clin. Experiment. Surg. Petrovsky J. 2016. № 2. Р. 35–46.
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