Central catheter-associated bloodstream infection in children with short bowel syndrome
Abstract Purpose. Catheter-associated bloodstream infection (CABSI) is one of the life-threatening complications for patients with short bowel syndrome (SBS). In this article, we present the algorithms of diagnostics, treatment and preventive therapy CABSI in patients requiring long-term parenteral nutritional support.
Materials and methods. We analyzed the CABSI frequency of 23 children with SBS at the time of initial admission to hospital, during hospitalization – before and after autologous intestinal reconstruction and on the stages of home parenteral nutrition (HPN). Seventeen cases of CABSI were diagnosed, the largest number of which had at the time of initial hospitalization (9), the least – on the stage of HPN (3). According to the etiology fungal infection was prevalented.
Results. Diagnostics and treatment protocols of CABSI allowed to stop a generalized inflammatory response in 15 patients with SBS in various stages of treatment. 3 patients died from CABSI at different stages after successfully performed autologous intestinal reconstruction.
Conclusion. Experience of prolonged parenteral nutrition, including HPN, allowed to develop measures of preventive treatment of catheter-related complications in children with SBS.
Keywords:catheter-associated bloodstream infection, children with short bowel syndrome, parenteral nKuetyrwitoiordnsa:l support, diagnostics, treatment
Clin. Experiment. Surg. Petrovsky J. 2016. № 2. Р. 96–103.
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