Long-term results after anatomic heart transplantation
Abstract
The article presents the analysis of major events of 18-year-long follow-up of a patient with
postinfarction myocardial dysfunction and ischemic cardiomyopathy after performing the original operation of orthotopic anatomical heart transplantation on six anastomoses. Special attention is paid to the original severe dyslipidemia, progressive on the background of active immunosuppressive therapy and the risk of occlusive coronary vessels of the transplant. Throughout
the follow-up period the patient was conducted sessions of plasmapheresis (3–4 times per year),
coronary angiography for the prevention of life-threatening graft dysfunction and biopsy with
electron-hystological control. In the discussion the authors analyze the need for personalized
diagnostics to select effective tactics of treatment of such patients, and pay attention to cancer
issues, which, along with post-transplant cardiomyopathy, are the major factors of postoperative
long-term mortality after orthotopic heart transplantation.
Keywords:рost-transplantation cardiomyopathy, anatomical heart transplantation, plasmapheresis after cardiac transplantation, oncological diseases in transplant patients, immunosuppressive therapy
Clin. Experiment. Surg. Petrovsky J. 2017; 5 (3): 60–4.
DOI: 10.24411/2308-1198-2017-00046
Received: 11.05.2017. Accepted: 15.06.2017.
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