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3 . 2018

The multidisciplinary approach to the problem of sudden cardiac death. The morphologist's view

Abstract

Definition, epidemiology, causes, initiating factors and mechanisms of sudden cardiac death, principles of interdisciplinary approach to the problem of sudden death, the main principles of genetic analysis and morphological study of the heart are described in the article.

Keywords:sudden cardiac death, causes and mechanisms, genetic and morphological study

Clin Experiment Surg. Petrovsky J. 2018; 6 (3): 16–24.

doi: 10.24411/2308-1198-2018-13002. Received: 05.05.2018. Accepted: 10.08.2018.

References

1. Makarov L.M., Solokhin Yu.A. Sudden out of hospital cardiac death in children, adolescents, and subjects younger than 45 years. Kardiologiya [Cardiology]. 2009; (11): 33–8. (in Russian)

2. Boitsov S.A., Linchak R.M., Nedbaikin A.M.,Sementsova E.V., et al. The epidemiology of sudden cardiac death. Klinicheskaya praktika [Clinical Practice]. 2014; (4): 13–8. (in Russian)

3. Gordeeva M.V., Mitrofanova L.B., Pakhomov A.V., Velesvlavova O.E., et al. Sudden cardiac death in adolescents and young adults. Vestnik aritmologii [Bulletin of Arrhythmology]. 2012; (68): 34–44. (in Russian)

4. Semsarian C., Ingles J., Wilde A.A. Sudden cardiac death in the young: the molecular autopsy and a practical approach to surviving relatives. Eur Heart J. 2015; 36 (21): 1290–6.

5. Basso C., Carturan E., Pilichou K., Rizzo S., et al. Sudden cardiac death with normal heart: molecular autopsy. Cardiovasc Pathol. 2010;19 (6): 321–5.

6. Shlyakhto E.V., Arutyunov G.P., Belenkov Yu.N., Ardashev A.V. National Recommendations on the definition of risk and prevention of sudden cardiac death. Arkhiv vnutrenney meditsiny [The Russian Archives of Internal Medicine]. 2013; (4): 5–15. (in Russian)

7. Zipes D.P., Camm A.J., Borggrefe M., Buxton A.E., et al. ACC/ AHA/ESC 2006 guidelines for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: a report of the American College of Cardiology/American Heart Association Task Force and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Develop Guidelines for Management of Patients with Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death) Developed in Collaboration with the European Heart Rhythm Association and the Heart Rhythm Society. Europace. 2006; 8 (9): 746–837.

8. Zipes D.P., Wellens H.J.J. Sudden cardiac death. Circulation. 1998; 98: 2334–51.

9. Ng B., Maginot K.R. Sudden cardiac death in young ath- letes: trying to find the needle in the haystack. WMJ. 2007; 106 (6): 335–42.

10. Winkel B.G., Holst A.G., Theilade J., Gaarsdal A., et al. Na- tionwide study of sudden cardiac death in persons aged 1–35 years. Eur Heart J. 2011; 32: 983–90.

11. Eckart R., Scoville S., Shry E., et al. Causes of sudden death in young female military recruits. Am J Cardiol. 2006; 97: 1756–8.

12. Eckart R., Scoville S., Campbell C., et al. Sudden death in young adults: a 25-year review of autopsies in military recruits. Ann Intern Med. 2004; 141: 829–34.

13. Ackerman M.J., Priori S.G., Willems S., et al. HRS/EHRA Expert Consensus Statement on the State of Genetic Testing for the Channelopathies and Cardiomyopathies. Europace. 2011; 13 (8): 1077–09.

14. Priori S.G, Blomstrom-Lundqvist C., Mazzanti A., Blom N., et al. ESC guidelines for the Management of Patients with ventricular arrhythmias and the prevention of sudden cardiac death: the task force for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death of the European Society of Cardiology (ESC). Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC). Eur Heart J. 2015; 36 (41): 2793–867.

15. Bagnall R.D., Weintraub R.G., Ingles J., Duflou J., et al A prospective study of sudden cardiac death among children and young adults. N Engl J Med. 2016; 374 (25): 2441–52.

16. Papadakis M., Raju H., Behr E.R., De Noronha S.V., et al. Sudden cardiac death with autopsy findings of uncertain significance: potential for erroneous interpretation. Circ Arrhythm Electrophysiol. 2013; 6 (3): 588–96.

17. Elliott P.M., Anastasakis A., Borger M.A., Borggrefe M., et al. ESC guidelines on diagnosis and management of hypertrophic cardiomyopathy: the task force for the diagnosis and Management of Hypertrophic Cardiomyopathy of the European Society of Cardiology (ESC). Eur Heart J. 2014; 35 (39): 2733–79.

18. Marcus F.I., McKenna W.J., Sherrill D., Basso C., et al. Diagnosis of arrhythmogenic right ventricular cardiomyopathy/dysplasia. Proposed modification of the Task Force Criteria. Circulation. 2010; 121 (13): 1533–41.

19. Larsen M.K., Nissen P.H., Kristensen I.B., Jensen H.K., et al. Sudden cardiac death in young adults: environmental risk factors and genetic aspects of premature atherosclerosis. J Forensic Sci. 2012; 57 (3): 658–62.

20. Nordestgaard B.G., Chapman M.J., Humphries S.E., Ginsberg H.N., et al. Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: consensus statement of the European Atherosclerosis Society. Eur Heart J. 2013; 34 (45): 3478–90.

21. Erbel R., Aboyans V., Boileau C., Bossone E., et al. 2014 ESC guidelines on the diagnosis and treatment of aortic diseases: document covering acute and chronic aortic diseases of the thoracic and abdominal aorta of the adult: the task force for the diagnosis and treatment of aortic diseases of the European Society of Cardiology (ESC). Eur Heart J. 2014; 35 (41): 2873–926.

22. Halushka M.K., Angelini A., Bartoloni G., Basso C., et al. Consensus statement on surgical pathology of the aorta from the Society for Cardiovascular Pathology and the Association for European Cardiovascular Pathology: II. Noninflammatory degenerative diseases – nomenclature and diagnostic criteria. Cardiovasc Pathol. 2016; 25 (3): 247–57.

23. Hiratzka L.F., Creager M.A., Isselbacher E.M., Svensson L.G., et al. 2010 ACCF/AHA/AATS/ACR/ASA/SCA/SCAI/SIR/STS/SVM guidelines for the diagnosis and management of patients with thoracic aortic disease. J Am Coll Cardiol. 2010; 55 (14): e27–129.

24. Henkin S., Negrotto S.M., Tweet M.S., Kirmani S., et al. Spontaneous coronary artery dissection and its association with heritable connective tissue disorders. Heart. 2016; 102 (11): 876–81.

25. De Stefano V., Rossi E. Testing for inherited thrombophilia and consequences for antithrombotic prophylaxis in patients with venous thromboembolism and their relatives. A review of the guidelines from scientific societies and working groups. Thromb Haemost. 2013; 110 (4): 697–705.

26. Goldman A.M., Behr E.R., Semsarian C., Bagnall R.D., et al. Sudden unexpected death in epilepsy genetics: molecular diagnostics and prevention. Epilepsia. 2016; 57 (1): 17–25.

27. Mitrofanova L.B. Cardiomyopathy. Working standards of morphological examination of the heart. Textbook for doctors. In: Library of the Pathologist. 2017; (175): 51 р. (in Russian)

28. Mitrofanova L.B., Mitrofanov N.A., Grokhotova V.V., Gordeeva M.V., et al. Arkhiv intravital and postmortem morphological studies and magnetic resonance imaging of arrhythmogenic right ventricular dysplasia. Arkhiv patologii [Archive of Pathology]. 2013; (6): 9–15. (in Russian)

29. Elliott P., Andersson B., Arbustini E., Bilinska Z., et al. Clas- sification of the cardiomyopathies: a position statement from the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases. Eur Heart. J. 2008; 29 (2): 270–6.

30. Caforio A.L., Pankuweit S., Arbustini E., Basso C., et al. Current state of knowledge on aetiology, diagnosis, management, and therapy of myocarditis: a position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases. Eur Heart J. 2013; 34 (33): 2636–48, 2648a–d.

31. Basso C., Aguilera B., Banner J., Cohle S., et al. Guidelines for autopsy investigation of sudden cardiac death: 2017 update from the Association for European Cardiovascular Pathology. Virchows Arch. 2017; 471 (6): 691–705.

32. Basso K., Aguilera B., Banner Yu., Kole Sh., et al. A guide to pathoanatomical examination of the heart in sudden cardiac death: an updated edition of the Association of European Cardiovascular Pathologists in 2017 (translated into Russian). URL: http://www.medline.ru/public/razdels/nmm/art_nmm_001.phtml. (in Russian)

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CHIEF EDITOR
CHIEF EDITOR
Sergey L. Dzemeshkevich
MD, Professor (Moscow, Russia)

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