To the content
1 . 2019

New approaches to risk stratification in elderly patients with heart surgery

Abstract

The problem of risk stratification in elderly patients undergoing elective cardiac surgery is still quite acute.
Aim – to analyze perioperative predictors of 30-day mortality in elective elderly cardiosurgical patients and to develop, on this results, original risk stratification models.

Material and methods. Our study included 127 patients (87 male and 40 female) in the age from 65 to 84 years (mean age 72.2±4.7 years). A wide range of perioperative factors was analyzed. The primary end point of the study was a 30-day mortality.

Results. Statistically significant perioperative predictors of the 30-day mortality were: the calculated values of the CAF scale (p<0.001) and EFI scale (p=0.001), the operation volume (p=0.044), the use of CPB during surgery (p=0.048). Based on frailty scale used in our study and positive predictors of 30-day mortality original scales were developed and compared with EuroScore II scale (p=0.676). Original scales had high prognostic value: original scale based on CAF (p<0.001); original scale based on EFI (p<0.001).

Conclusion. Using of frailty scores and based on it original models allows you to accurately predict 30-day mortality in elderly patients.

Keywords:cardiac surgery, surgery, aging, frailty index

For citation: Shikhverdiev N.N., Ushakov D.I., Peleshok A.S., Krivopalov V.A., Sizenko V.V. New approaches to risk stratification in elderly patients with heart surgery. Clin Experiment Surg. Petrovsky J. 2019; 7 (1): 27–7. doi: 10.24411/2308-1198- 2019-11003. (in Russian)
Received 27.06.2018. Accepted 06.02.2019.

References

1. Shihverdiev N.N., Peleshok A.S., Ushakov D.I., Krivopalov V.A., Samedov Ya.S., Sizenko V.V. Effect of frailty in outcomes of patients undergoing cardiac surgery. Vestnik Rossiyskoy voenno-meditsinskoy akademii [Bulletin of the Russian Military Medical Academy]. 2017; 3 (59): 18–21. (in Russian)

2. Shikhverdiev N.N., Ushakov D.I., Luk'yanov N.G. Assessment ofbiological age in a heart surgery. Grudnaya i serdechno-sosudistaya khirurgiya [Thoracic and Cardiovascular Surgery]. 2017; 1: 20–7. (in Russian)

3. Graham M., et al. Frailty and Outcome in Elderly Patients With Acute Coronary Syndrome. Can J Card. 2013; 29: 1610–15.

4. Abdullahi Y.S., Athanasopoulos L.V., Casula R.P., Moscarelli M., Bagnall M., Ashrafian H., Athanasiou T. Systematic review on the predictive ability of frailty assessment measures in cardiac surgery. Interact Cardiovasc Thorac Surg. 2017; 24: 619–24.

5. Afilalo J., Mottillo S., Eisenberg M.J., et al. Addition of frailty and disability to cardiac surgery risk scores identifies elderly patients at high risk of mortality or major morbidity. Circ Cardiovasc Qual Outcomes. 2012; 5: 222–8.

6. Clegg A., Young J., Iliffe S., et al. Frailty in elderly people. Lancet. 2013; 381: 752–62.

7. Schoenenberger A.W., Stortecky S., Neumann S., et al. Predictors of functional decline in elderly patients undergoing transcatheter aortic valve implantation (TAVI). Eur Heart J. 2013; 34: 684–92.

8. Sepehri A., Beggs T., Hassan A., et al. The impact of frailty on outcomes after cardiac surgery: a systematic review. J Thorac Cardiovasc Surg. 2014; 148 (6): 3110–7.

9. Kuwaki K., Inaba H., Yamamoto T., et al. Performance of the EuroSCORE II and The Society of Thoracic Surgeons score in patients undergoing aortic valve replacement for aortic stenosis. J Cardiovasc Surg. 2015; 56: 455–62.

10. Vahanian A., Alfieri O., Andreotti F., et al. Joint Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology, European Association for CardioThoracic Surgery. Guidelines on the management of valvular heart disease (version 2012). Eur Heart J. 2012; 33: 2451–96.

11. Sündermann S., Dademasch A., Praetorius J., et al. Comprehensive assessment of frailty for elderly high-risk patients undergoing cardiac surgery. Eur J Cardiothorac Surg. 2011; 39 (1): 33–7.

All articles in our journal are distributed under the Creative Commons Attribution 4.0 International License (CC BY 4.0 license)

CHIEF EDITOR
CHIEF EDITOR
Sergey L. Dzemeshkevich
MD, Professor (Moscow, Russia)

Journals of «GEOTAR-Media»