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1 . 2019

The immediate results of surgical treatment of the mitral valve dysplasia

Abstract

Aim. To analyze the resuls of surgical treatment of the patients with mitral valve dysplasia (MVD) and to evaluate the outcome taking into account the surgical approach (plasty or replacement).

Material and methods. A retrospective analysis of the clinical records of the 250 patients with mitral valve dysplasia and clinical manifestation of the mitral regurgitation (MR) was performed. All patients underwent surgical treatment by mitral valve plasty or replacement from 2009 to 2016 in the Federal Center for Cardiovascular Surgery (Astrakhan).

Results. Patients with MVD had severe MR (tearing off the posterior leaflet was the commonest feature), with echocardiographic and clinical signs of the mitral valve disease. The histological anlysis of the leaflets revealed myxomatous disorganization of collagen fibers with the formation of fibrosis in 100% cases. Plasty of the MV was performed in 194 pts (77.6%), MV replacement – in 56 pts (22.4%). All patients had a satisfactory condition at the time of discharge, 244 pts (97.6%) had MR degree 0–I post-operatively, and 4 (1.6%) had MR of 2 degree.

Conclusion. Surgical treatment should be recommended for patients with MR and mitral valve dysplasia before manifestation of the pathological cardiac remodelling (decreasing of the ejection fraction, left atrium enlargement, and atrial fibrillation). The obtained direct results of the surgery of the analyzed patient group correspond to the literary, worldwide data. The successful restoration of the MV function by a surgical method is possible both MV repair and MV replacement. MV repair is preferable to valve replacement.

Keywords:mitral valve, mitral regurgitation, mitral valve dysplasia, mitral valve plasty, mitral valve replacement

For citation: Martyanova Yu.B., Kondratiev D.A., Markova M.M., Zaklyazminskaya E.V., Tarasov D.G. The immediate results of surgical treatment of the mitral valve dysplasia. Clin Experiment Surg. Petrovsky J. 2019; 7 (1): 28–33. doi: 10.24411/2308- 1198-2019-11004. (in Russian)
Received 05.09.2018. Accepted 06.02.2019.

References

1. Enriquez-Sarano M., Akins C.W., Vahanian A. Mitral regurgitation. Lancet. 2009; 373: 1382–94.

2. Rumyantseva V.A., Zaklyazminskaya E.V. The genetics of mitral valve prolapse (analytical review). Clin Experiment Surg. Petrovsky J. 2013; 2: 47–55. (in Russian)

3. Chahal A.A., Bouatia-Naji N. Genetics of mitral valve prolapse and clinical impact. E-J Cardiol Pract. 2018; 16 (35).

4. Dzemshkevich S.L., Stevenson L.U. Diseases of the mitral valve. 2nd ed. Moscow: GEOTAR-Media, 2015. (in Russian)

5. Sayeed R. Mitral valve disease when should we call in the cardiac surgeon. E-Journal Cardiol Pract. 2018; 16 (28).

6. EI Sabbagh A., Reddy Y.N.V., Nishimura R.A. Mitral valve regurgitation in the contemporary era: Insights into diagnosis, management and future directions. JACC Cardiovasc Imaging. 2018; 11: 628–43.

7. Ling L.H., Enriquez-Sarano M., Sevard J.B., Orszulak T.A., et al. Early surgery in patients with mitral regurgitation due to flail leaflets: a long-term outcome study. Circulation. 1997; 96: 1819–25.

8. Castillo J.G., Anyanwu A.C., Fuster V., Adams D.H. A near 100% repair rate for mitral valve prolapse is achievable in a reference center: implications for future guidelines. J Thorac Cardiovasc Surg. 2012; 144: 308–12.

9. Salustri A., Almaghrabi A. Mitral valve disease correlation between the most important echocardiographic parameters and haemodynamics. E-Journal Cardiol. Pract. 2018; 16 (24).

10. Rana B.S., Lee J.M., Nihoyannopoulos P. 3D echocardiography in mitral valve disease – is the new gold standard? Eur Cardiol. 2010; 6: 61–6.

11. Baumgartner H., Falk V., Bax J.J., De Bonis M., et al. 2017E ESC/EACTS Guidelines for management of valvular heart disease. Eur Heart J. 2017; 38: 2739– 91.

12. Athanasiou T., Chow A., Rao C., Aziz O., et al. Preservation of mitral valve apparatus: evidence synthe- sis and reappraisal of surgical techniques. Eur J Cardiothorac Surg. 2008; 33: 391–401.

13. Coutinho G.F., Antunes M.J. Mitral valve repair for degenerative mitral valve disease surgical: approach, patient selection and long-term outcomes. Heart. 2017; 103: 1663–9.

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CHIEF EDITOR
CHIEF EDITOR
Sergey L. Dzemeshkevich
MD, Professor (Moscow, Russia)

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