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2 . 2021

Immediate results of implantation of a modified composite frame xenopericardial bioprosthesis in the aortic position

Abstract

The aim of this study is to assess the immediate hemodynamic characteristics of the biological modified prosthesis MedInzh-BIO with the "easy change" system.

Material and methods. From October 2016 to December 2018 81 patients underwent surgery - aortic valve replacement using the MedInzh-BIO biological xenopericardial prosthesis (group 1). From January 2019 to January 2020, 44 patients underwent implantation of the modified MedInzh-BIO bioprosthesis (group 2). The effective orifice area (EPO) of the affected aortic valve in degenerative lesions did not exceed, as a rule, 1.0 cm2. The peak pressure gradient was increased to an average of 85.8±29.6 and 79.0±23.6 mm Hg, average gradient up to 50.1±18.7 and 45.9±15.5 mm Hg in group 1 and group 2, respectively. The combined interventions for aortic valve replacement in both groups did not differ significantly.

Results. When comparing hemodynamic parameters in patients in the group with modified prostheses, the peak and average gradients were significantly lower. EPO of MedInzh-BIO valves in group 1, size 21, was 0.91 cm2, size 23 - 1.2 cm2, size 25 - 1.3 cm2. In patients in the group after modification of the MedInzh-BIO 21 prosthesis, the EPO size was 1.02 cm2, size 23 - 1.3 cm2, size 25 - 1.6 cm2.

Conclusion. Comparative statistical analysis shows that in the group of patients with modified Meding-BIO prostheses, hemodynamic parameters are reliably better, prostheses have a higher EPO and iEPO than in patients with a prosthesis before modification.

Keywords:aortic valve, aortic valve replacement, bioprosthesis

Funding. The reported study was funded by RFBR, project number 20-315-90079/20. 
Conflict of interest. The authors declare no conflict of interest.
For citation: Kozlov B.N., Petlin K.A., Kosovskikh E.A., Vrublevsky A.V., Arsenyeva Yu.A. Immediate results of implantation of a modified composite frame xenopericardial bioprosthesis in the aortic position. Clinical and Experimental Surgery. Petrovsky Journal. 2021; 9 (2): 7-13. DOI: https://doi.org/10.33029/2308-1198-2021-9-2-7-13 (in Russian)

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CHIEF EDITOR
CHIEF EDITOR
Sergey L. Dzemeshkevich
MD, Professor (Moscow, Russia)

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