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3 . 2021

Features of left ventricular deformation properties in patients with coronary arteries

Abstract

Background. Modern imaging methods such as Speckle tracking echocardiography (STE) with the assessment of global longitudinal myocardial deformation have recently begun to play a key role in the diagnosis, prognosis and treatment tactics in patients with cardiovascular diseases. Aim - to study the deformation properties of the left ventricular myocardium in patients with coronary artery disease with varying degrees of damage to the coronary vessel.

Material and methods. The prospective study included 74 patients with stable angina pectoris (SAP) II-IV FC, aged 40 to 70 years, among them 49 (66.2%) were men and 25 (33.8%) - women. The indicators of the Global Longitudinal Strain and Strain Rate in relation to the results of coronary angiography were assessed. The patients were divided into three groups according to the Syntax Score scale: low risk (up to 22 points), medium risk (23-32) and high risk (>32 points).

Results demonstrate the diagnostic value of the deformation properties of the left ventricular myocardium in a comprehensive assessment of the severity of coronary vascular lesions, their relationship with the clinical course of the disease (a history of myocardial infarction). Along with the value of EF and EDV, indicators of longitudinal deformity (GLS and SR) have prognostic value in the diagnosis of the severity of coronary artery disease and coronary atherosclerosis. Comparative analysis of the deformation properties of the LV myocardium in the three studied groups showed that in high-risk patients, the indicators of GLS and the SR of the myocardium are significantly lower than in the groups of patients with low and intermediate risk (p=0.000). A similar picture was observed in terms of the rate of myocardial deformation SR (p=0.001).

Conclusion. Assessment of GLS and SR during transthoracic echocardiography in patients with coronary artery disease increases the informative value of the technique in assessing the degree of coronary artery disease and clearly demonstrates the relationship of these changes as markers of atherosclerosis progression in patients with coronary artery disease.

Keywords:speckle tracking echocardiography, global longitudinal deformation of the left ventricle, strain rate, coronary atherosclerosis, Syntax Score scale

Funding. The study had no sponsor support.
Conflict of interest. The authors declare no conflict of interest.
For citation: Fozilov Kh.G., Shek A.B., Bekmetova F.M., Alieva R.B., Mukhamedova M.G., Mullabaeva G.U., Doniyorov Sh.N., Ilkhomova L.T., Bekmetova S.I., Khotamova M.N. Features of left ventricular deformation properties in patients with coronary arteries. Clinical and Experimental Surgery. Petrovsky Journal. 2021; 9 (3): 118-24. DOI: https://doi.org/10.33029/2308-1198-2021-9-3-118-124 (in Russian)

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CHIEF EDITOR
CHIEF EDITOR
Sergey L. Dzemeshkevich
MD, Professor (Moscow, Russia)

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