3, Приложение . 2021

Surgical treatment of isolated total anomalous pulmonary venous connection in newborns: risk factors and results

Abstract

Background. Despite improving of surgical results of total anomalous pulmonary venous connection (TAPVC), newborns with TAPVC are still a challenge. In this report we analyze risk factors and our surgical results of treatment of isolated TAPVC in newborns.

Material and methods. In this retrospective study 40 newborns with TAPVC operated from 2004 to 2018 were included. The mean age of the admitted patients was 12.3±11 days, weight - 3.4±0.5 kg, saturation - 81.8±8.7%. All patients were treated by traditional surgical repair (direct veno-atrial anastomosis).

Results. From 40 newborns with TAPVC, 25 (62.5%) had hospitalization in ICU, 19 (47.5%) patients had artificial ventilation, 11 (27.5%) - inotropic support, preoperatively. The analysis of preoperative blood gas probes showed correlation between lactate level and preoperative artificial ventilation (p=0.007), inotropic support (p=0.03) and obstructive pulmonary blood flow (p=0.02). The such preoperative factors as age, weight, ICU hospitalization, inotropic support, obstructive pulmonary blood flow correlated (p<0.05) with postoperative course, which also correlated with bypass time, using of hypothermia and circulatory arrest. Operative mortality in newborns with TAPVC was 5%.

Conclusion. The surgical treatment of newborns with TAPVC can be achieved with good results and low mortality. The identified risk factors influence on postoperative course significantly, but this impact can be decreased by in-time surgical repair.

Keywords:total anomalous pulmonary venous connection, newborns

Funding. The study had no sponsor support.
Conflict of interest. The authors declare no conflict of interest.
For citation: Morozov A.A., Movsesyan R.R., Pervunina T.M., E.V. Grekhov E.V., Fedorova N.V., Latypov A.K., Vasichkina E.S. Surgical trestment of isolated total anomalous pulmonary venous connection in newborns: risk fartors and results. Clinical and Experimental Surgery. Petrovsky Journal. 2021; 9 (3): 82-9. DOI: https://doi.org/10.33029/2308-1198-2021-9-3suppl-82-89 (in Russian)

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