Comparative changes in some indicators of homeostasis in patients with postoperative ventral hernias
Abstract
Background. One of the tasks when using mesh implants in
herniology is to improve their biocompatibility. The search continues to
optimize the reparative process, with a decrease in the number of
postoperative complications.
Aim - to study a number of homeostasis indicators in patients with
postoperative ventral hernias using polypropylene and titanium mesh implants.
Material and methods. The analysis of clinical and laboratory results was
performed in 25 patients with incisional ventral hernias, who underwent
hernioplasty using a mesh "titanium silk" and 24 patients in
whom a polypropylene mesh was used. On the 1st and 5th days
after the operation, the indices of endogenous intoxication, oxidative
stress, phospholipase activity and general hypoxia were assessed.
Results. When using a polypropylene implant in patients in the
first 2 days after surgery, moderate disorders of homeostasis indicators were
noted. From the third day of the postoperative period, there was a
tendency for these processes to subside, and by the 4-5th day -
to their normalization. During hernioplasty using titanium silk, changes
in homeostasis in the early postoperative period were less pronounced.
This is probably due to the greater biological inertness of the titanium
mesh implant.
Conclusion. The biological inertness of "titanium silk"
leads to less pathological reactions of the body in the early postoperative
period.
Keywords:postoperative ventral hernia, polypropylene mesh, "titanium silk", homeostasis
Funding. The study had no sponsor support.
Conflict of interest. The authors declare no conflict of interest.
For citation: Azimov R.H., Gorsky V.A., Vlasov A.P., Glushkov P.S.,
Madrakhimov Sh.N., Okynev N.A. Comparative changes in some indicators of
homeostasis in patients with postoperative ventral hernias. Clinical and
Experimental Surgery. Petrovsky Journal. 2021; 9 (4): 105-10. DOI: https://doi.org/10.33029/2308-1198-2021-9-4-105-110 (in Russian)
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