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4 . 2021

Comparative changes in some indicators of homeostasis in patients with postoperative ventral hernias

Abstract

Background. One of the tasks when using mesh implants in herniology is to improve their biocompatibility. The search continues to optimize the reparative process, with a decrease in the number of postoperative complications.

Aim - to study a number of homeostasis indicators in patients with postoperative ventral hernias using polypropylene and titanium mesh implants.

Material and methods. The analysis of clinical and laboratory results was performed in 25 patients with incisional ventral hernias, who underwent hernioplasty using a mesh "titanium silk" and 24 patients in whom a polypropylene mesh was used. On the 1st and 5th days after the operation, the indices of endogenous intoxication, oxidative stress, phospholipase activity and general hypoxia were assessed.

Results. When using a polypropylene implant in patients in the first 2 days after surgery, moderate disorders of homeostasis indicators were noted. From the third day of the postoperative period, there was a tendency for these processes to subside, and by the 4-5th day - to their normalization. During hernioplasty using titanium silk, changes in homeostasis in the early postoperative period were less pronounced. This is probably due to the greater biological inertness of the titanium mesh implant.

Conclusion. The biological inertness of "titanium silk" leads to less pathological reactions of the body in the early postoperative period.

Keywords:postoperative ventral hernia, polypropylene mesh, "titanium silk", homeostasis

Funding. The study had no sponsor support.
Conflict of interest. The authors declare no conflict of interest.
For citation: Azimov R.H., Gorsky V.A., Vlasov A.P., Glushkov P.S., Madrakhimov Sh.N., Okynev N.A. Comparative changes in some indicators of homeostasis in patients with postoperative ventral hernias. Clinical and Experimental Surgery. Petrovsky Journal. 2021; 9 (4): 105-10. DOI: https://doi.org/10.33029/2308-1198-2021-9-4-105-110 (in Russian)

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CHIEF EDITOR
CHIEF EDITOR
Sergey L. Dzemeshkevich
MD, Professor (Moscow, Russia)

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