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3 . 2022

Medium-term results of aortic valve replacement with biological prosthesis: a single-centre retrospective study

Abstract

Aim – to analyze the medium-term results of aortic valve (AV) replacement with a biological prosthesis in our center of cardiovascular surgery.

Material and methods. 528 patients with AV pathology [269 men (51%)/259 women (49%)] were included in the retrospective study. Inclusion criteria: patients aged ≥18 years who underwent aortic valve replacement with a biological prosthesis. Exclusion criteria: prosthetics of ≥2 valves. The median age was 65 [62–70] years. There were 25 (4.7%) patients with infective endocarditis, and 61 (11.6%) had bicuspid AV. The median follow-up period was 37.8 [2.2–77.4] months.

Results. Combined interventions were performed in 87 (16.5%) cases. Hospital mortality was 1.1%. In the early postoperative period, 14 (2.7%) patients were indicated for implantation of a permanent pacemaker due to conduction disturbances. 2 (0.4%) patients developed perioperative myocardial injury, the number of strokes was 8 (1.5%). 10-year overall survival, freedom from cardiovascular death, stroke, freedom from reoperation, freedom from prosthetic infective endocarditis, freedom from degeneration were 58, 84.6, 93.3, 77.7, 95.1 and 87.2% respectively. By the end of the observation period, the median of the peak and average gradient on the biological prosthesis was 32 (25–40) and 18 (14–25) mm Hg, and aortic regurgitation ≥2 degree was detected in 10 (5%) patients.

Conclusion. The long-term survival and durability of Braile Biomedica, SJM Biocor biological prostheses are the same as for any other biological prosthesis available.

Keywords:aortic stenosis; aortic regurgitation; acquired heart disease; aortic valve replacement; aortic valve; biological prosthesis

Funding. The study had no sponsor support.
Conflict of interest. The authors declare no conflict of interest.
For citation: Enginoev S.T., Kondratyev D.A., Tsaroev B.S., Мagomedov G.M., Rashidova T.K., Abdurahmanov A.A., Аbdulmedzhidova U.K., Ziankou A.A., Chernov I.I., Tarasov D.G. Medium-term results of aortic valve replacement with biological prosthesis: a single-centre retrospective study. Clinical and Experimental Surgery. Petrovsky Journal. 2022; 10 (3): 28–37. DOI: https://doi.org/10.33029/2308-1198-2022-10-3-28-37  (in Russian)

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CHIEF EDITOR
CHIEF EDITOR
Sergey L. Dzemeshkevich
MD, Professor (Moscow, Russia)
Вскрытие
Medicine today

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