Medium-term results of aortic valve replacement with biological prosthesis: a single-centre retrospective study
Aim – to analyze the medium-term results of aortic valve
(AV) replacement with a biological prosthesis in our center of cardiovascular
Material and methods. 528 patients with AV pathology [269 men (51%)/259
women (49%)] were included in the retrospective study. Inclusion criteria:
patients aged ≥18 years who underwent aortic valve replacement with a
biological prosthesis. Exclusion criteria: prosthetics of ≥2 valves. The median
age was 65 [62–70] years. There were 25 (4.7%) patients with infective
endocarditis, and 61 (11.6%) had bicuspid AV. The median follow-up period was
37.8 [2.2–77.4] months.
Results. Combined interventions were performed in 87 (16.5%)
cases. Hospital mortality was 1.1%. In the early postoperative period, 14
(2.7%) patients were indicated for implantation of a permanent pacemaker due to
conduction disturbances. 2 (0.4%) patients developed perioperative myocardial
injury, the number of strokes was 8 (1.5%). 10-year overall survival, freedom
from cardiovascular death, stroke, freedom from reoperation, freedom from
prosthetic infective endocarditis, freedom from degeneration were 58, 84.6,
93.3, 77.7, 95.1 and 87.2% respectively. By the end of the observation period,
the median of the peak and average gradient on the biological prosthesis was 32
(25–40) and 18 (14–25) mm Hg, and aortic regurgitation ≥2 degree was detected
in 10 (5%) patients.
Conclusion. The long-term survival and durability of Braile
Biomedica, SJM Biocor biological prostheses are the same as for any other
biological prosthesis available.
Keywords:aortic stenosis; aortic regurgitation; acquired heart disease; aortic valve replacement; aortic valve; biological prosthesis
Funding. The study had no sponsor support.
Conflict of interest. The authors declare no conflict of interest.
For citation: Enginoev S.T., Kondratyev D.A., Tsaroev B.S.,
Мagomedov G.M., Rashidova T.K., Abdurahmanov A.A., Аbdulmedzhidova U.K.,
Ziankou A.A., Chernov I.I., Tarasov D.G. Medium-term results of aortic valve
replacement with biological prosthesis: a single-centre retrospective study.
Clinical and Experimental Surgery. Petrovsky Journal. 2022; 10 (3): 28–37. DOI:
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