Patients with favorable and unfavorable outcomes of cardiac surgical revascularization: morphological and morphometric characteristics of the heart (clinical cases)
Abstract
The article presents
a description of two identified cases of coronary heart disease with a decrease
in the frequency of left ventricular events and multivessel atherosclerotic
lesions of the coronary arteries. A comprehensive diagnostic examination of
patients using modern imaging techniques, features of surgical treatment are
described. The results of morphological and morphometric studies of heart
biopsy specimens from patients with initial substances of surgical treatment
were analyzed.
Keywords:ischemic heart disease; reduced left ventricular ejection fraction; coronary artery bypass grafting; morphometry; inflammatory vascular infiltration
Funding. The study had no sponsor support.
Conflict of interest. The authors declare no conflict of interest.
For citation: Shipulin V.M., Andreev S.L., Garganeeva A.A., Pryakhin
A.S., Shipulin V.V., Stelmashenko A.I., Beliaeva S.A., Kuzheleva E.A., Karpov
R.M. Patients with favorable and unfavorable outcomes of cardiac surgical
revascularization: morphological and morphometric characteristics of the heart
(clinical cases). Clinical and Experimental Surgery. Petrovsky Journal. 2022;
10 (4): 46–50. DOI: https://doi.org/10.33029/2308-1198-2022-10-4-46-50
(in Russian)
References
1. Clinical practice guidelines for Stable coronary artery disease. 2020. (in Russian)
2. Bolognese L., Neskovic A.N., Parodi G., Cerisano G., Buonamici P., Santoro G.M., et al. Left ventricular remodeling after primary coronary angioplasty. Circulation. 2002; 106 (18): 2351–7.
3. Shipulin V.M., Gutor S.S., Sukhodolo I.V., Borisova L.V., Andreev S.L., Katkov V.A. Morphological and molecular indicators of the state of the myocardium: prognosis of outcomes of surgical treatment of patients with ischemic cardiomyopathy. Clinical and Experimental Surgery. Petrovsky Journal. 2015; (1): 5–14. (in Russian)
4. Shipulin V.V., Saushkin V.V., Pryakhin A.S., Andreev S.L., Vesnina Zh.V., Zavadovsky K.V. Possibilities of myocardial perfusion scintigraphy in the examination of patients with ischemic cardiomyopathy. Rossiyskiy elektronniy zhurnal luchevoy diagnostiki [Russian Electronic Journal of Radiation Diagnostics]. 2019; 9 (3): 155–75. (in Russian)
5. Nikolaos G.F. The extracellular matrix in ischemic and nonischemic heart failure. Circ Res. 2019; 125: 117–46.
6. Avtandilov G.G. Medical morphometry. Moscow: Meditsina, 1990: 367–84. (in Russian)