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2 . 2023

The use of minimally invasive technologies of lithotripsy and antegrade hydraulic lithoextraction in the complex treatment of patients with choledocholithiasis complicated by obstructive jaundice and cholangitis

Abstract

Actuality. Сholedocholithiasis is one of the most common complications of cholelithiasis. The gold standard for the treatment of choledocholithiasis at the present stage is minimally invasive retrograde endoscopic and videolaparoscopic methods of treatment. However, according to various authors, the incidence of so-called «difficult choledocholithiasis», when the above methods cannot be applied technically or are ineffective, ranges from 10 to 15% cases of choledocholithiasis.

Aim. To evaluate the effectiveness of the use of minimally invasive technologies of lithotripsy and antegrade hydraulic lithoextraction in the complex treatment of patients with choledocholithiasis complicated by obstructive jaundice and cholangitis.

Material and methods. In the main group, consisting of 18 patients with choledocholithiasis complicated by obstructive jaundice and cholangitis, а complex treatment was carried out using minimally invasive technologies of lithotripsy and hydraulic antegrade lithoextraction. In the comparison group, which included 35 patients with choledocholithiasis complicated by obstructive jaundice and cholangitis, complex treatment was carried out without the use of minimally invasive lithotripsy technologies and hydraulic antegrade lithoextraction.

Results. During treatment, patients in both groups demonstrated statistically significant decrease in laboratory parameters of bilirubinemia, cytolysis and cholestasis against the background of the elimination of clinical manifestations of obstructive jaundice. At the same time, in the comparison group, there were statistically significant post-inflammatory strictures and cicatricial stenoses of the choledochus. The main proportion of these complications accounted for laparotomic interventions, such as external drainage of the choledochus according to Ker and Vishnevsky, which were avoided in the main group due to the use of minimally invasive lithotripsy technologies and antegrade hydraulic lithoextraction.

Conclusion. Minimally invasive technologies of lithotripsy and antegrade hydraulic lithoextraction are safe alternatives to traditional methods of lithoextraction and can be recommended for use in patients in whom video-laparoscopic and retrograde endoscopic lithoextraction are ineffective, especially in the case of cholangitis as a risk factor for the development of post-inflammatory strictures and cicatricial stenosis of the choledochus.

Keywords:choledocholithiasis; minimally invasive lithotripsy; antegrade hydraulic lithoextraction; obstructive jaundice; cholangitis

Funding. The study had no sponsor support.

Conflict of interest. The authors declare no conflict of interest.

For citation: Tseimakh A.E., Kurtukov V.A., Mishchenko A.N., Tepluhin V.N., Shoikhet Ya.N., Tseimakh M.E. The use of minimally invasive technologies of lithotripsy and antegrade hydraulic lithoex-traction in the complex treatment of patients with choledocholithiasis complicated by ob-structive jaundice and cholangitis. Clinical and Experimental Surgery. Petrovsky Journal. 2023; 11 (2): 34–40. DOI: https://doi.org/10.33029/2308-1198-2023-11-2-34-40  (in Russian)

References

1.     Tanaja J., Lopez R.A., Meer J.M. Cholelithiasis. 2021. In: StatPearls [Electronic resource]. Treasure Island, FL: StatPearls Publishing, 2022. PMID: 29262107.

2.     McNicoll C.F., Pastorino A., Farooq U., St Hill C.R. Choledocholithiasis. 2021. In: StatPearls [Electronic resource]. Treasure Island, FL: StatPearls Publishing, 2022. PMID: 28722990.

3.     Tringali A., Costa D., Fugazza A., Colombo M., Khalaf K., Repici A., et al. Endoscopic management of difficult common bile duct stones: Where are we now? A comprehensive review. World J Gastroenterol. 2021; 27 (44): 7597–611. DOI: https://doi.org/10.3748/wjg.v27.i44.7597  

4.     Manes G., Paspatis G., Aabakken L., Anderloni A., Arvanitakis M., Ah-Soune P., et al. Endoscopic management of common bile duct stones: European Society of Gastrointestinal Endoscopy (ESGE) guideline. Endoscopy. 2019; 51 (5): 472–91. DOI: https://doi.org/10.1055/a-0862-0346  

5.     ASGE Standards of Practice Committee; Buxbaum J.L., Abbas Fehmi S.M., Sultan S., Fishman D.S., Qumseya B.J., Cortessis V.K., et al. ASGE guideline on the role of endoscopy in the evaluation and management of choledocholithiasis. Gastrointest Endosc. 2019; 89 (6): 1075–105.e15. DOI: https://doi.org/10.1016/j.gie.2018.10.001  

6.     Cianci P., Restini E. Management of cholelithiasis with choledocholithiasis: Endoscopic and surgical approaches. World J Gastroenterol. 2021; 27 (28): 4536–54. DOI: https://doi.org/10.3748/wjg.v27.i28.4536   

7.     Wu Y., Xu C.J., Xu S.F. Advances in risk factors for recurrence of common bile duct stones. Int J Med Sci. 2021; 18 (4): 1067–74. DOI: https://doi.org/10.7150/ijms.52974  

8.     Wang L., Yu W.F. Obstructive jaundice and perioperative management. Acta Anaesthesiol Taiwan. 2014; 52 (1): 22–9. DOI: https://doi.org/10.1016/j.aat.2014.03.002  

9.     EASL Clinical Practice Guidelines on the prevention, diagnosis and treatment of gallstones. J Hepatol. 2016; 65: 146–81. DOI: https://doi.org/10.1016/j.jhep.2016.03.005

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CHIEF EDITOR
CHIEF EDITOR
Sergey L. Dzemeshkevich
MD, Professor (Moscow, Russia)

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