Basilar artery thrombosis in young ages due to erythrocytosis. Clinical case

• Kuznetsova P.I.
• Sinycyn I.A.
• Morozova S.N.
• Raskurazhev А.А.
• Shabalina A.A.
• Salimov K.A.
• Pisetsky P.B.
• Tanashyan M.M.

Abstract

The manuscript describes a clinical case of a 37-year-old patient with the development of vertebral and basilar artery thrombosis and stroke in the setting of erythrocytosis.

Keywords: erythrocytosis, stroke; endovascular thromboextraction; basilar artery thrombosis

References

1.     Fairbanks V.F., Tefferi A. Normal ranges for packed cell volume and hemoglobin concentration in adults: relevance to «apparent polycythemia». Eur J Haematol. 2000; 65: 285–96.

2.     Arber D.A., Orazi A., Hasserjian R., et al. The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia. Blood. 2016; 127: 2391–405.

3.     Tefferi A., Barbui T. Polycythemia vera and essential thrombocythemia: 2021 update on diagnosis, risk stratification and management. Am J Hematol. 2020; 95: 1599–613.

4.     Arber D.A., Orazi A., Hasserjian R.P., et al. International Consensus Classification of myeloid neoplasms and acute leukemias: integrating morphologic, clinical, and genomic data. Blood. 2022; 140: 1200–28.

5.     Wouters H., Mulder R., van Zeventer I.A., et al. Erythrocytosis in the general population: clinical characteristics and association with clonal hematopoiesis. Blood Adv. 2020; 4: 6353–63.

6.     Tremblay D., Alpert N., Taioli E., Mascarenhas J. Prevalence of unexplained erythrocytosis and thrombocytosis – an NHANES analysis. Leuk Lymphoma. 2021; 62: 2030–3.

7.     WHO Classification of Tumours of Lymphoid and Hematopoietic Tissues. Lyon: IARC, 2017. 585 p.

8.     Gangat N., Pardanani A., Tefferi A. Erythrocytosis associated with cerebral hemangiomas and multiple venous anomalies. Am J Hematol. 2020; 95 (10): 1224–5. DOI: https://doi.org/10.1002/ajh.25913

9.     Leblanc G.G., Golanov E., Awad I.A., Young W.L.; Biology of Vascular Malformations of the Brain NINDS Workshop Collaborators. Biology of vascular malformations of the brain. Stroke. 2009; 40 (12): e694–702. DOI: https://doi.org/10.1161/STROKEAHA.109.563692 Epub 2009 Oct 15.

10. Nguyen E., Harnois M., Busque L., Sirhan S., Assouline  S., Chamaki I., et al. Phenotypical differences and thrombosis rates in secondary erythrocytosis versus polycythemia vera. Blood Cancer J. 2021; 11 (4): 75. DOI: https://doi.org/10.1038/s41408-021-00463-x  

11. Fahrurriza H., Gofir A., Setyawan T.R., Hutajulu S.H., Nugroho D.B., Ar Rochmah M. Concomitant cerebral venous thrombosis and intracranial hemorrhages in presentation of a patient with secondary polycythemia: a case report. Am J Case Rep. 2023; 24: e941507. DOI: https://doi.org/10.12659/AJCR.941507

All articles in our journal are distributed under the Creative Commons Attribution 4.0 International License (CC BY 4.0 license)